The SCALA Study changes from a 2-arm to a 4-arm design
The project has taken the decision jointly to change the SCALA study design from 2 to 4 study arms, in order to be able to give more precise information about what works (and what doesn't) in increasing screening and brief interventions in primary care for alcohol and co-morbid depression.
The 4-arm study design will compare centres with and without municipal support and with a long version vs a short version of the trainig and implementation programme.
The reasons for adopting a 4-arm study design in scala are the following:
- Outcome of discussions with country partners (part of tailoring and adaptation) to simplify components of SCALA, including clinical package and training package;
- Alignment with objectives of SCALA, whose aim is to increase chances of scale-up in resource-constrained countries;
- Provide for first time scientific answer to question of whether implementation and penetration of screening and advice and treatment programmes is higher when the package to be scaled is simpler and shorter rather than more complex and longer;
- The decision is aligned with evidence that briefer advice programmes are as effective as longer ones.
The study arms will consequently be:
Arm 1: Control - no training or municipal action
Arm 2: Control with training (short version)
Arm 3: Intervention - Municipal action plan + short training/intervention package
Arm 4: Intervention - Municipal action plan + long training/intervention package